AI-based Integration of Genetic and Environmental Information to Determine Risk for Multiple Sclerosis
Location: Salon 7
Speaker: Sergio E. Baranzini, PhD – Weill Institute for Neurology Heidrich Family and Friends, Institute for Human Genetics, Graduate Program in Bioinformatics
10:25 AM - 10:40 AM PST
A Multi-ethnic Reference Map of TCR Germline Diversity Reveals Evidence of Natural Selection on Variable and Joining Alpha Chain Genes
Engineering Immunosuppression-resistant Allogeneic CD19 CAR T cells to Treat B cell-driven Autoimmune Disorders Without the Need for Glucocorticoid Weaning
Location: Salons 3-6
Presenting Author: Viktor Glaser – Charité - Universitätsmedizin Berlin
Immuno-engineering and Cellular Therapies
11:20 AM - 11:45 AM PST
Fine-Tuning Dendritic Cell Function to Overcome Tumor Immune Escape
Increased Glutamine Dependence of CD8 T cells in Human Critical Illness Drives Dysregulated Effector and Exhausted-Like Programming and Associates With Poor Clinical Outcomes
Location: Salons 3-6
Presenting Author: Casey M. Nichols – Vanderbilt University Medical Center
A Treg Cell-targeted IL-2m Results in Superior Suppression of Th2 Responses Compared to CD25-biased IL-2m and anti-IL4R Blockade in a Mouse Model of Asthma
Defining the Immunological Features of CD19 CAR T cell Therapy in MRL/lpr Mice
Location: Salon 7
Presenting Author: Tatiana Lau – University of British Columbia
Autoimmune Diseases
4:45 PM - 5:00 PM PST
Collagen-disrupting TIL-cell Therapy for Sarcoma
Location: Salon 7
Presenting Author: Shulin Li, PhD – The University of Texas MD Anderson Cancer Center
Immuno-engineering and Cellular Therapies
5:00 PM - 5:15 PM PST
CNP-104, an Antigen-Specific Tolerogenic Nanoparticle Therapy, Stabilizes Prognostic Trajectory and Liver Stiffness with a Link to Reduction in Pathogenic T-Cells in Primary Biliary Cholangitis
Non-ICANS Neurotoxicity Following BCMA CAR T-cell Therapy: Distinguishing Movement and Neurocognitive Toxicity from Peripheral Nervous System Manifestations